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Allele : Btg4<em3Hyfn> BTG anti-proliferation factor 4; endonuclease-mediated mutation 3, Heng-Yu Fan

Primary Identifier  MGI:6276547 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Btg4
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 mutagenesis was used to create mutations in codon 95 to alter the codon to encode an alanine instead of a tryptophan (W95A). This mutation was shown in vitro to abolish interactions with Cnot7 and Cnot8. An altered protein is detectable in oocytes derived from mutant mice.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Btg4<W95A>,
  • Btg4<W95A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele