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Allele : Tg(RP11-578M14)5Mkru transgene insertion 5, M Katharine Rudd

Primary Identifier	MGI:6273991	Allele Type	Transgenic
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Tg(RP11-578M14)5Mkru
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

The transgene consists of BAC RP11-578M14 (184 kb) containing 14 human genes (GNB3, MLF2, CD4, PTMS, LAG3, COPS7A, GPR162, P3H3 (LEPREL2), CDCA3, USP5, TPI1, SPSB2, RPL13P5, and DSTNP2) from 12p13.31, including the T variant of GNB3. Lines 5, 4 and 3 were generated.

mutations:
Insertion

synonyms:
GNB3-T,
GNB3-T,
GNB3,
GNB3

earliestPublication:
Goldlust IS, et al. (2013) Mouse model implicates GNB3 duplication in a childhood obesity syndrome. Proc Natl Acad Sci U S A 110(37):14990-4

1 Feature

Genome

12 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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