| Primary Identifier | MGI:6260167 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Itm2c |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A null allele was generated using CRISPR/Cas9-mediated gene deletion. Guide RNAs were designed to target intronic sequences flanking exons 2 and 5, resulting in the deletion of the intervening exons. No mRNA transcripts were detected in lipopolysaccharide (LPS) stimulated B cell cultures from homozygous mutant mice. |
