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Allele : Tg(CAG-IL1A)#Takm transgene insertion, Takeshi Miyamoto

Primary Identifier  MGI:6274747 Allele Type  Transgenic
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Tg(CAG-IL1A)#Takm
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene construct that was micro-injected into fertilized eggs conatins the following elements: the CAG promoter-enhancer, a loxP site flanked neomycin resistance gene cassette (which includes p(A) sequences), and the human interleukin 1 alpha gene. This creates a conditional-ready allele where the human gene is only expressed after the deletion of the neo cassette through cre-mediated recombination.
  • mutations:
  • Insertion
  • synonyms:
  • hIL-1 cTg,
  • hIL-1 cTg
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories