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Allele : Mir33<em1Cfh> microRNA 33; endonuclease-mediated mutation 1, Carlos Fernandez-Hernando

Primary Identifier	MGI:6280346	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Mir33
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 mediated excision of Mir33 was accomplished using targeted guide sequences toward intron 16 of the Srebf2 gene.

mutations:
Intragenic deletion

synonyms:
miR-33<->,
miR-33<->

earliestPublication:
Price NL, et al. (2018) Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance. Cell Rep 22(8):2133-2145

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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