| Primary Identifier | MGI:6275065 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Dominant negative, Inserted expressed sequence, Reporter | Gene | Tg(ACTB-EGFP,-Kcnj8*)1Wco |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene consists of the chicken beta-actin (CX1) promoter, followed by a loxP-flanked EGFP gene including a stop codon, and a pore rat Kcnj8 dominant negative mutant in which glycine-phenylalanine-glycine was mutated to three alanines. EGFP is ubiquitously expressed unless cre-recombinase is expressed which excises the EGFP and results in expression of the mutant Kcnj8. Three lines were generated but only a single line was selected for further study. |
