| Primary Identifier | MGI:6272384 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Smcr8 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A 26-bp deletion of chromosome 11 (60,778,048-60,778,073) in exon 1 of Smcr8 was created using the CRISPR/Cas9 system and sgRNA 5'-GGGATCTTCGTCTTCTGACG-3'. This deletion result in a predicted frameshifted protein product beginning after amino acid 7 of the protein and terminating after the inclusion of six aberrant amino acids. |
