| Primary Identifier | MGI:6272643 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Dclk2 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCTCCTGGAAGTAATCCTAG and GCAGTCTACGTAATTGAGAA, which resulted in a 736 bp deletion beginning at Chromosome 3 position 86,905,679 bp and ending after 86,906,414 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000409228 (exon 2) and 404 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 141 and early truncation 10 amino acids later. |
