| Primary Identifier | MGI:6272647 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Syt8 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCTACTACTGTAGCTTCCAA and CTAGGCCTTTCCCTGAAAAA, which resulted in a 1829 bp deletion beginning at Chromosome 7 position 142,438,739 bp and ending after 142,440,567 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001253691 through ENSMUSE00000668076 (exons 4-9) and 834 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 97 and early truncation 44 amino acids later. |
