| Primary Identifier | MGI:6272656 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Tacr3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CACACGCTAAAGAATCTTAT and GACATTCGCAGACCTTCCAA, which resulted in a 398 bp deletion beginning at Chromosome 3 position 134,861,032 bp and ending after 134,861,429 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000176975 (exon 3) and 247 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 233 and early truncation 1 amino acid later. |
