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Allele : Tg(K14-Il33)1Kyam transgene insertion 1, Kiyofumi Yamanishi

Primary Identifier	MGI:6272799	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(K14-Il33)1Kyam
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

A 2-kb human keratin 14 promoter (GenBank accession no. AB091380.1), drives the transcription of a 0.6-kb 0.8-kb full-coding sequence of mouse IL-33 variant 1 cDNA. Two transgenic lines were established, but only one was studied further.

mutations:
Insertion

synonyms:
hK14mIL33tg,
hK14mIL33tg

earliestPublication:
Imai Y, et al. (2013) Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice. Proc Natl Acad Sci U S A 110(34):13921-6

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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