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Allele : Mre11a<tm3.1Dof> MRE11A homolog A, double strand break repair nuclease; targeted mutation 3.1, David O Ferguson
Primary Identifier  MGI:6272743 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Mre11a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 10 along with 181 intronic bases upstream and 234 bases downstream were replaced with a loxP-flanked neomycin resistance cassette. The neo was removed via cre-mediated recombination. RT-PCR and sequencing confirmed the expression of the shorter 9-11 splice variant RNA.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mre11<ASM>,
  • Mre11<ASM>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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