Primary Identifier | MGI:6281378 | Allele Type | Targeted |
Gene | Map4k1 | Transmission | Germline |
Strain of Origin | C57BL/6NTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The targeting vector inserted an ATGGAA to GCGGAG mutation in exon 4 (includes a silent mutation to remove an EcoRI site) resulting in a methionine to a substitution at amino acid 91 (M91A) and a FRT-flanked PGK1-neomycin cassette. Flp-mediated recombination in ES cells removed the selection cassette. |