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Allele : Map4k1<tm2.1Gne> mitogen-activated protein kinase kinase kinase kinase 1; targeted mutation 2.1, Genentech

Primary Identifier  MGI:6281378 Allele Type  Targeted
Gene  Map4k1 Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  The targeting vector inserted an ATGGAA to GCGGAG mutation in exon 4 (includes a silent mutation to remove an EcoRI site) resulting in a methionine to a substitution at amino acid 91 (M91A) and a FRT-flanked PGK1-neomycin cassette. Flp-mediated recombination in ES cells removed the selection cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Map4k1 M91A,
  • Map4k1 M91A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele