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Allele : Del(15Rr38-Rr313939)7Fsp deletion, Chr 15, Francois Spitz 7
Primary Identifier  MGI:6281724 Allele Type  Transposon induced
Attribute String  Conditional ready, Modified regulatory region, Reporter Gene  Del(15Rr38-Rr313939)7Fsp
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.184347Fsp at chr15:62708842-62708843 (GRCm39) and Tn(sb-SBlac)15.179039Fsp at chr15:63590844-63590845 deleted approximately 882 kb and leaves one intact copy of the transposon cassette (in forward orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD) and contains Myc enhancers Rr38, Rr334, Rr316124, Rr313933, Rr331, Rr307328, Rr332, Rr307330, Rr333 and Rr313939.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • del(8-17),
  • del(8-17),
  • Del(15-TgTn(sb-SBlac)15.184347Fsp-TgTn(sb-SBlac)15.179039Fsp)1Fsp,
  • Del7Fsp,
  • Del(15-TgTn(sb-SBlac)15.184347Fsp-TgTn(sb-SBlac)15.179039Fsp)1Fsp,
  • Df(184347-179039),
  • Df(184347-179039),
  • Del7Fsp
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1 Feature

Genome

0 Expresses

22 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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