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Allele : Slc17a2<em1(IMPC)J> solute carrier family 17 (sodium phosphate), member 2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6294082 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc17a2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAGGGTTCTTAGTTAGTAG and CCTACATCAGTCAAAGGCTG, which resulted in a 640 bp deletion beginning at Chromosome 13 position 23,814,821 bp and ending after 23,815,460 bp (GRCm38/mm10). This mutation deletes ENSMUSE0000124538 and ENSMUSE00001248222 (exons 4 and 5) and 318 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 80 and early truncation 14 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories