Primary Identifier | MGI:6294096 | Allele Type | Targeted |
Attribute String | Modified regulatory region | Gene | Rr95 |
Transmission | Germline | Strain of Origin | (129 x C57BL/6)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Homologous recombination with a targeting vector removed 365 bp containing Cd4 maturation enhancer E4m in Cd4 intron 1 and inserted a loxP site flanked neomycin resistance gene cassette upstream of neighboring Cd4 silencer S4 (Rr96). The neo cassette was removed through subsequent cre-mediated recombination. |