| Primary Identifier | MGI:6281109 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Clptm1l |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| molecularNote | Cre-mediated recombination of Clptm1ltm1c(EUCOMM)Wtsi removed exon 3, creating a frame shift mutation with a stop codon immediately downstream. No mRNA transcripts were detected in lipopolysaccharide (LPS) stimulated B cell cultures from homozygous mutant mice. Interestingly, the abundance of mRNA was greater in heterozygous B cell cultures than in wild-type cultures. |
