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Allele : Hdac9<em1Birn> histone deacetylase 9; endonuclease-mediated mutation 1, Ramon Y Birnbaum

Primary Identifier	MGI:6294466	Allele Type	Endonuclease-mediated
Attribute String	Modified regulatory region, Null/knockout	Gene	Hdac9
Inheritance Mode	Not Specified	Strain of Origin	C57BL
Is Recombinase	false	Is Wild Type	false

molecularNote

Using CRISPR/Cas technology, a 23 kb sequence in the Hdac9 gene containing all three enhancers eTw5-7 (Rr134-Rr136) of the Twist1 gene and exons 17-20 of Hdac9 gene (23,137bp; chr12:34883773-34906909; mm9) was removed.

mutations:
Intragenic deletion

synonyms:
eTw5-7 delta,
eTw5-7 delta

earliestPublication:
Hirsch N, et al. (2018) Unraveling the transcriptional regulation of TWIST1 in limb development. PLoS Genet 14(10):e1007738

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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