| Primary Identifier | MGI:6294748 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Piezo2 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGGGGCTCATTTCAACCTAA and CCTTGACGTTGGAAAGCCAA, which resulted in a 417 bp deletion beginning at Chromosome 18 position 63,030,224 bp and ending after 63,030,640 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001304790 (exon 42) and 164 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 2106 and early truncation 15 amino acids later. |
