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Allele : Noxred1<em1(IMPC)J> NADP+ dependent oxidoreductase domain containing 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6294782 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Noxred1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGAGCATGCCTAACTCCAAG and AGGAAGCAGCTTAAGTCACG, which resulted in a 337 bp deletion beginning at Chromosome 12 position 87,224,804 bp and ending after 87,225,140 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000114055 (exon 5) and 156 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause an early truncation after amino acid 119.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories