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Allele : Pcdhg<em34Rwb> protocadherin gamma cluster; endonuclease-mediated mutation 34, Robert W Burgess

Primary Identifier  MGI:6285827 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Pcdhg
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was generated through shotgun CRISPR/Cas9 editing using pooled sgRNAs that targeted each variable exon of the Pcdhg cluster and this allele was found to have a frameshift disrupting the variable exon A10, in-frame mutations in variable exons B5 and B6, and structural rearrangements impacting exons A1 through A5.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele