| Primary Identifier | MGI:6286098 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Themis |
| Inheritance Mode | Dominant | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3866 |
| molecularNote | ENU-induced T to A transversion at base pair 28,781,832 (v38) on chromosome 10, or base pair 113,506 in the GenBank genomic region NC_000076 encoding Themis. The mutation corresponds to residue 1,154 in the mRNA sequence NM_178666 within exon 4 of 6 total exons. The mutation results in a valine to glutamic acid substitution at position 285 (V285E) in the Themis protein. |
