| Primary Identifier | MGI:6314340 | Allele Type | Targeted |
| Attribute String | Conditional ready, Humanized sequence | Gene | Rac1 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector is designed to insert a loxP-flanked STOP cassette, containing a neomycin resistance cassette, upstream of exon 2 of the gene. Exon 2 was modified to harbor a missense mutation at codon 29, resulting in a proline to serine mutation (P29S) commonly found in patients with cutaneous melanoma. |
