Primary Identifier | MGI:6305853 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Dock2 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4364 |
molecularNote | A to C transversion at base pair 34,262,445 (v38) on chromosome 11, or base pair 521,465 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 3,777 in the mRNA sequence NM_178666 within exon 37 of 52 total exons. The mutation results in an aspartic acid to alanine substitution at position 1,232 (D1232A) in the DOCK2 protein. |