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Allele : Dock2<M16Btlr> dedicator of cyto-kinesis 2; mutation 16, Bruce Beutler

Primary Identifier  MGI:6305853 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Dock2
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4364
molecularNote  A to C transversion at base pair 34,262,445 (v38) on chromosome 11, or base pair 521,465 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 3,777 in the mRNA sequence NM_178666 within exon 37 of 52 total exons. The mutation results in an aspartic acid to alanine substitution at position 1,232 (D1232A) in the DOCK2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • harborside,
  • harborside
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories