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Allele : Card11<M6Btlr> caspase recruitment domain family, member 11; mutation 6, Bruce Beutler

Primary Identifier  MGI:6283989 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Card11
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3708
molecularNote  ENU-induced C to T transition at base pair 140,876,425 (v38) on chromosome 5, or base pair 124,172 in the GenBank genomic region NC_000071 encoding Card11. The mutation corresponds to residue 3,437 in the mRNA sequence NM_175362 within exon 23 of 25 total exons. The mutation results in a proline to leucine substitution at position 1,039 (P1039L) in the CARMA1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Sharp,
  • Sharp
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele