Primary Identifier | MGI:6283989 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Card11 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3708 |
molecularNote | ENU-induced C to T transition at base pair 140,876,425 (v38) on chromosome 5, or base pair 124,172 in the GenBank genomic region NC_000071 encoding Card11. The mutation corresponds to residue 3,437 in the mRNA sequence NM_175362 within exon 23 of 25 total exons. The mutation results in a proline to leucine substitution at position 1,039 (P1039L) in the CARMA1 protein. |