Primary Identifier | MGI:6287437 | Allele Type | Endonuclease-mediated |
Gene | Cenpf | Strain of Origin | (C57BL/6 x DBA/2)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology introduced a TT to GC mutation in exon 17 resulting in a phenylalanine to alanine substitution at amino acid 2872 (F2872A). This mutation is within the Rhot (Miro)-binding region and is predicted to abolish Rhot-binding. |