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Allele : Cenpf<em1Bko> centromere protein F; endonuclease-mediated mutation 1, Benoit Kornmann

Primary Identifier  MGI:6287437 Allele Type  Endonuclease-mediated
Gene  Cenpf Strain of Origin  (C57BL/6 x DBA/2)F1
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology introduced a TT to GC mutation in exon 17 resulting in a phenylalanine to alanine substitution at amino acid 2872 (F2872A). This mutation is within the Rhot (Miro)-binding region and is predicted to abolish Rhot-binding.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • CENP-F<F2872A>,
  • cenpf<[p.F872A]BKL>,
  • CENP-F<F2872A>,
  • cenpf<[p.F872A]BKL>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories