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Allele : Cfap418<em1(IMPC)J> cilia and flagella associated protein 418; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6294893 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cfap418
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGTGCTGTCACTCTAGCAGT and TGAGGAGTACAGGTAAAGAA, which resulted in a 505 bp deletion beginning at Chromosome 4 position 10,879,214 bp and ending after 10,879,718 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001279296 (exon 2) and 417 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 52 and early truncation 53 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories