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Allele : Rag1<m4Btlr> recombination activating 1; mutation 4, Bruce Beutler

Primary Identifier  MGI:6283875 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Rag1
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  A to T transversion at base pair 101,642,710 (v38) on chromosome 2, or base pair 6,823 in the GenBank genomic region NC_000068. The mutation corresponds to residue 2,211 (c.2211A>T) in the mRNA sequence NM_009019.2 within exon 2 of 2 total exons. The mutation results in an arginine to tryptophan substitution at position 696 (p.R696W) in the RAG1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • defective,
  • defective
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories