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Allele : Itpa<em#Drf> inosine triphosphatase (nucleoside triphosphate pyrophosphatase); endonuclease-mediated mutation, David R FitzPatrick

Primary Identifier  MGI:6287401 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Itpa
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology was used to generate a null allele. Sequencing revealed several null alleles including c.-33_125_129delinsCTGTCTGTTT, c.-33_125_147del, c.258dupC, and c.234_257del, however the # is used as no line is specified and/or lines are pooled. Western blot analysis confirmed absence of protein in homozygotes.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories