| Primary Identifier | MGI:6283518 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Ubac1 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTAATTGGGTGTTCTAGTAG and GCAGATTTAAGCAAGTTTGT, which resulted in a 873 bp deletion beginning at Chromosome 2 position 26,008,577 bp and ending after 26,009,449 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001223421 and ENSMUSE00000236713 (exons 5 and 6) and 661 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 147 and early truncation 11 amino acids later. |
