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Allele : Dock2<M14Btlr> dedicator of cyto-kinesis 2; mutation 14, Bruce Beutler

Primary Identifier  MGI:6285155 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Dock2
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4068
molecularNote  ENU-induced G to A transition at base pair 34,256,562 (v38) on chromosome 11, or base pair 527,348 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 4,115 in the mRNA sequence NM_178666 within exon 40 of 52 total exons. The mutation results in a glycine to arginine substitution at position 1,345 (G1345R) in the DOCK2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Launch,
  • Launch
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories