Primary Identifier | MGI:6285155 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Dock2 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4068 |
molecularNote | ENU-induced G to A transition at base pair 34,256,562 (v38) on chromosome 11, or base pair 527,348 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 4,115 in the mRNA sequence NM_178666 within exon 40 of 52 total exons. The mutation results in a glycine to arginine substitution at position 1,345 (G1345R) in the DOCK2 protein. |