| Primary Identifier | MGI:6285167 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Ptpn6 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3820 |
| molecularNote | ENU-induced A to G transition at base pair 124,724,984 (v38) on chromosome 6, or base pair 13,726 in the GenBank genomic region NC_000072. The mutation corresponds to residue 1,535 in the mRNA sequence NM_013545 within exon 11 of 16 total exons. The mutation results in a histidine to arginine substitution at position 445 (H445R) in variant 1 of the SHP1 protein. |
