| Primary Identifier | MGI:6307777 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Prss3b |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| description | C57BL/6 embryonic stem (ES) cells (Cyagen, Santa Clara, CA) |
| molecularNote | Exon 2 was modified to produce the amino acid substitution of alanine for aspartic acid at position 23 (D23A). This mutation autoactivates to trypsin 50-fold faster than wild type. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted into intron 1. |
