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Allele : Prss3b<tm1.1Satom> serine protease 3B; targeted mutation 1.1, Miklos Sahin-Toth
Primary Identifier  MGI:6307777 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Prss3b
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
description  C57BL/6 embryonic stem (ES) cells (Cyagen, Santa Clara, CA)
molecularNote  Exon 2 was modified to produce the amino acid substitution of alanine for aspartic acid at position 23 (D23A). This mutation autoactivates to trypsin 50-fold faster than wild type. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted into intron 1.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • T7<D23A>,
  • T7<D23A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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