| Primary Identifier | MGI:6284319 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Nkpd1 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCTCCCTGAGAAAGGATGGG and GCTGAAGTTGGCATCCCAGG, which resulted in a 2325 bp deletion beginning at Chromosome 7 position 19,522,850 bp and ending after 19,525,174 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000476801 (exon 4) and 245 bp of flanking intronic sequence including the splice acceptor and is predicted to cause a change of amino acid sequence after residue 224 and early truncation 71 amino acids later. |
