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Allele : Dock2<m10Btlr> dedicator of cyto-kinesis 2; mutation 10, Bruce Beutler

Primary Identifier  MGI:6284832 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Dock2
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3732
molecularNote  ENU-induced A to C transversion at base pair 34,732,371 (v38) on chromosome 11, or base pair 51,539 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 276 in the mRNA sequence NM_178666 within exon 4 of 52 total exons. The mutation results in a histidine to proline substitution at position 65 (H65P) in the DOCK2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • wharf,
  • wharf
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories