Primary Identifier | MGI:6284832 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Dock2 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3732 |
molecularNote | ENU-induced A to C transversion at base pair 34,732,371 (v38) on chromosome 11, or base pair 51,539 in the GenBank genomic region NC_000077 for Dock2. The mutation corresponds to residue 276 in the mRNA sequence NM_178666 within exon 4 of 52 total exons. The mutation results in a histidine to proline substitution at position 65 (H65P) in the DOCK2 protein. |