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Allele : Prss3b<tm2.1Satom> serine protease 3B; targeted mutation 2.1, Miklos Sahin-Toth

Primary Identifier  MGI:6307817 Allele Type  Targeted
Attribute String  Not Specified Gene  Prss3b
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was modified to produce the amino acid substitution of alanine for aspartic acid at position 23 (D23A) and glycine for lysine at position 24 (K24G) to abolish trypsinogen activation. Cre-mediated recombination removed the floxed neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • T7 D23A,K24G,
  • T7 D23A,K24G
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories