| Primary Identifier | MGI:6285541 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Dock8 |
| Inheritance Mode | Dominant | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3735 |
| molecularNote | ENU-induced T to C transition at base pair 25,149,831 (v38) on chromosome 19, or base pair 150,321 in the GenBank genomic region NC_000085 encoding Dock8. The mutation corresponds to residue 3,294 in the mRNA sequence NM_028785 within exon 26 of 48 total exons. The mutation results in a tyrosine to histidine substitution at position 1,058 (Y1058H) in the DOCK8 protein. |
