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Allele : Myh8<em1(IMPC)Tcp> myosin, heavy polypeptide 8, skeletal muscle, perinatal; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6302756 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Myh8
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR1302 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CTGGTTCATAGAGGGCTAGG and CCTAACTCCTACATTATCAC targeting the 5' side and TCCACTTTAGGATGTGAACG and GAACTTTTTTGTATCCAAGT targeting the 3' side of a critical region. This resulted in a 729-bp del Chr11:67279720-67280448_insT and 6-bp del Chr11:67279605-67279610 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories