| Primary Identifier | MGI:6303744 | Allele Type | Targeted |
| Gene | Map4k1 | Transmission | Germline |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A point mutation was engineered in exon 2, changing lysine codon 46 to methionine (p.K46M). The FRT site flanked puromycin resistance gene cassette that was inserted into intron 5 was removed through subsequent flp-mediated recombination. The amino-acid substitution in the kinase domain of the encoded peptide creates a kinase-dead protein. |
