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Allele : Lmbr1l<em1Btlr> limb region 1 like; endonuclease-mediated mutation 1, Bruce Beutler

Primary Identifier  MGI:6303829 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Lmbr1l
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The CRISPR/Cas9 system and sgRNA 5'-TGCACTCGCGGACCCTGTCG-3' was used to generate the mice. The CRISPR/Cas9 system generated a 2-base pair deletion at c.231_232del (NM_029098.3). The mutation is predicted to cause a frame-shifted protein product beginning after amino acid 17 of the protein and premature termination after the inclusion of 30 aberrant amino acids.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories