Primary Identifier | MGI:6331132 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence, Reporter | Gene | Tg(Ctsl-Gdnf/EGFP)1Reb |
Strain of Origin | (C57BL/6J x C3H/HeJ)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A mouse Gdnf cDNA was cloned in-frame with the EGFP from the Pem212 clone, where human MT2A intron 1 was inserted into the EGFP coding region at nucleotide 898. The Pem promoter was then replaced by the Cathepsin L KpnI-SalI promoter/intron 1 fragment from a luciferase reporter construct. One of six characterized transgenic lines was used for further analysis. |