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Allele : Tecrl<em1(IMPC)J> trans-2,3-enoyl-CoA reductase-like; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6303609 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tecrl
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTGTAGGTCTTAAACTCCAA and TAGACAGTCTTTAGCATTAG, which resulted in a 471 bp deletion beginning at Chromosome 5 position 83,309,187 bp and ending after 83,309,657 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000403078 (exon 4) and 367 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 109 and early truncation 3 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories