| Primary Identifier | MGI:6303989 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Unc93b1 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The CRISPR/Cas9 system and sgRNA 5'-AGGAAGTCCCAACCAGCTGC-3' was used to generate the mice. The CRISPR/Cas9 system generated a 109-base pair deletion at c.138_28del (NM_019449.2). The mutation is predicted to cause a frame-shifted protein product beginning after amino acid 7 of the protein and premature termination after the inclusion of 63 aberrant amino acids. |