| Primary Identifier | MGI:6314202 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Hps5 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGAGTCGTCACCTCTCCCTG and TTACATTGTGTCCCGGGCAG, which resulted in a 690 bp deletion beginning at Chromosome 7 position 46,788,692 bp and ending after 46,789,381 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001284002, ENSMUSE00001285409 (exons 3 and 4) and 514 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 36 and early truncation 46 amino acids later. |
