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Allele : Tg(Tbx6-cre)#Rsam transgene insertion, Ramkumar Sambasivan

Primary Identifier  MGI:6331071 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Tbx6-cre)#Rsam
Strain of Origin  Not Specified Is Recombinase  true
Is Wild Type  false
molecularNote  Using a bacterial artificial chromosome (BAC), transgene was created such that the cre recombinase is driven by Tbx6 regulatory sequences. The Cre recombinase expression cassette was inserted into into a bacterial artificial chromosome (BAC; clone# RP24239G12) containing Tbx6 locus with approximately 84 Kb upstream, 4 Kb of the open reading frame and 73 Kb downstream sequences at the 1st exon of Tbx6 such that 14 nucleotides (25th to 39th bases) including the ATG are removed. Four lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • Tbx6-Cre,
  • Tbx6-Cre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

2 Publication categories