Primary Identifier | MGI:6331094 | Allele Type | Endonuclease-mediated |
Attribute String | Recombinase | Gene | Dmrt3 |
Strain of Origin | B6D2F1 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Zinc finger nuclease mRNAs designed for the Dmrt3 locus, and a donor vector carrying iCre and 2A peptide sequence were introduced to B6D2F1 zygotes by pronuclear microinjection. The 2A peptide coding sequence allows for cotranslation of the Dmrt3 promoter-driven iCre followed by Dmrt3. |