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Allele : Rr102<tm1.2Ics> regulatory region 102; targeted mutation 1.2, Mouse Clinical Institute

Primary Identifier  MGI:6336135 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr102
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT site flanked neomycin resistance cassette and a loxP site flanked chicken transcriptional enhancer element A that contains specific mutations in the Egr2 binding sites that prevent binding of wild-type Egr2 and instead allow binding of a mutant Egr2 protein, and an F3-flanked mouse element A replaced the wild-type Egr2 autoregulatory element A. Flp-mediated recombination removed the F3 flanked mouse element A and the neo cassette and cre-mediated recombination removed the floxed chicken element A.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Krox20<deltaA>,
  • Egr2<tm1.2Ics>,
  • Krox20<deltaA>,
  • Egr2<tm1.2Ics>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories